Platelet-derived growth factors analyzers SEB-C100
Product sumo
Iyo Platelet Derived Growth Factor Analyzer ndeye yekuyedza uye yekuongorora yakavakirwa pane yakasarudzika nzira yekuyedza inopayona nekambani yedu.Iyo analyzer inoona platelet-yakatorwa kukura factor, chaiyo protein marker muweti yemunhu inogadzirwa kana coronary artery stenosis ikaitika.Kuongorora kunogona kupedzwa mumaminitsi mashomanana nekushandisa 1ml chete yeweti.Iyo analyzer inogona kuona kana iyo coronary arteries ine stenosis uye dhigirii re stenosis kuitira kuti ipe referensi yekuwedzera kuongororwa.Nzira yekuona uye yekuongorora yeplatelet-derived growth factor analyzer ndiyo yepakutanga isiri-invasive yekuona nzira, iyo isingade majekiseni nemishonga yekubatsira, kubvisa dambudziko rekuti vanhu vanopesana ne-iodine-ine zvakasiyana-siyana vamiririri havakwanisi kuita CT uye mamwe coronary. artery angiography.Iyo analyzer ine mabhenefiti emutengo wakaderera wekuyedza, kuwanda kwekushandisa, nyore kushandisa, kukurumidza kuyedza kumhanya, nezvimwewo, uye imhando nyowani ye coronary artery stenosis yekutanga kuona uye kuongorora chiridzwa.
Iyo analyzer ine zvinotevera zvakanakira:
1. Kukurumidza: Isa weti mumudziyo wekuona uye ingomirira maminetsi mashoma
2. Kubatsira: Kuongororwa hakungowanikwi muzvipatara chete.Zvinogona zvakare kuitwa kunzvimbo dzekuongorora kurapwa, kudzimba dzevakoti kana kudzimba dzenharaunda
3. Nyaradzo: 1ml chete yeweti inodiwa semuenzaniso, hapana ropa rinokwevera, hapana mushonga, hapana majekiseni akasiyana, hapana kunetseka nezve allergic reaction.
4. Intelligence: Kunyatsoongorora otomatiki, kushanda pane isina kutarisirwa
5. Easy einstallation: Diki size, inogona kuiswa uye kushandiswa nehafu yetafura
6. Kugadzirisa kuri nyore: Kungotarisa otomatiki uye kunoratidza mamiriro ekushandisa kuitira nyore kushandiswa kutsiva
Nheyo yechigadzirwa
Raman spectroscopy inoshandisa kupararira kwechiedza kukurumidza kuongorora chimiro chemolecular.Iyi nzira inobva pamusimboti wekuti kana chiedza chikavheneka molecule, kudhumhana kwe elastic kunoitika uye chikamu chechiedza chinopararira.Kuwanda kwechiedza chakapararira kwakasiyana nekuwanda kwechiedza chechiitiko, chinozivikanwa seRaman kuparadzira.Kusimba kweRaman kuparadzira kushamwaridzana nechimiro chemorekuru, zvichibvumira kuongororwa kwese kusimba kwayo uye kuwanda kwayo kuona chimiro uye chimiro chemorekuru chaizvo.
Nekuda kwekusasimba kwechiratidzo cheRaman uye kazhinji kukanganiswa kwefluorescence, kuwana Raman spectra panguva yekuonekwa chaiko kunogona kunetsa.Kunyatsoona chiratidzo cheRaman kwakaoma zvechokwadi.Naizvozvo, iyo yepamusoro yakakwidziridzwa yeRaman spectroscopy inogona kuwedzera zvakanyanya kusimba kweRaman yakapararira mwenje, kugadzirisa nyaya idzi.Nheyo yakakosha yetekiniki iyi inosanganisira kuisa chinhu kuti chionekwe panzvimbo yesimbi, sesirivha kana goridhe.kuitira kugadzira nzvimbo yakakasharara, nanometer-level, zvichikonzera kukwidziridzwa kwepamusoro.
Zvakaratidzwa kuti Raman spectrum yemarker platelet-derived growth factor (PDGF-BB) yakaratidza peak yakasiyana pa1509 cm-1.Kupfuurirazve, zvakasimbiswa kuti kuvepo kweiyo marker platelet-derived growth factor (PDGF-BB) muweti yakabatana ne coronary artery stenosis.
Nekushandisa Raman spectroscopy uye pamusoro pekusimudzira tekinoroji, iyo PDGF analyzer inogona kuyera kuvepo kwePDGF-BB uye hunhu hwayo hwepamusoro 'kusimba muweti.Izvi zvinogonesa kutsunga kwekuti coronary arteries ndeye stenotic uye dhigirii re stenosis, zvichipa hwaro hwekuongororwa kwekiriniki.
Background yechigadzirwa
Mumakore achangopfuura, kuwanda kwechirwere chemoyo chiri kuwedzera zvishoma nezvishoma nekuda kwekuchinja kwekudya uye mararamiro emararamiro, pamwe chete nekukwegura kwevanhu.Nhamba yekufa inobatanidzwa nehosha yemwoyo inoramba ichikwira zvinotyisa.Sekureva kweChina Cardiovascular Health and Disease Report 2022, huwandu hwekufa kwechirwere chemoyo pakati pevagari vemumaguta ekuChina huchasvika 126.91/100,000 uye 135.88/100,000 pakati pevagari vekumaruwa muna 2020. Huwandu uhwu hwanga huchikwira kubva 2012 nekuwedzera kukuru kumaruwa.Muna 2016, yakapfuura iyo yepamusoro yeguta uye yakaramba ichikwira muna 2020. Parizvino, coronary arteriography ndiyo nzira yekutanga yekuongorora inoshandiswa mumakiriniki ekugadzirisa chirwere chemoyo.Kunyange ichinzi "yegold standard" yekuongororwa kwechirwere chemoyo, kupindira kwayo uye mutengo wakakwira zvakakonzera kugadzirwa kweelectrocardiography seimwe nzira yekuongorora zvishoma nezvishoma.Kunyangwe electrocardiogram (ECG) kuongororwa kuri nyore, kuri nyore, uye kusingadhure, kusaziva uye kusiiwa kwekuongororwa kunogona kuitika, zvichiita kuti isavimbike pakuongororwa kwekiriniki kwechirwere chemoyo.Nokudaro, kugadzirwa kwenzira isina-invasive, yakanyanya kujeka, uye yakavimbika yekukurumidza uye nekukurumidza kuona kwechirwere chemwoyo inokosha zvikuru.
Surface-enhanced Raman spectroscopy (SERS) yakawana kushandiswa kwakapararira musainzi yehupenyu yekuona biomolecules pakadzika zvakanyanya.Somuenzaniso, Alula et al.vakakwanisa kuona maminetsi emazinga e creatinine muweti nekushandisa SERS spectroscopy ine foto catalytically modified silver nanoparticles ine magineti zvinhu.
Saizvozvowo, Ma et al.akashandisa magineti akakonzeresa kuunganidzwa kwenanoparticles muSERS spectroscopy kuratidza yakaderera zvakanyanya yedeoxyribonucleic acid (DNA) mubhakitiriya.
Platelet-derived growth factor-BB (PDGF-BB) inoita basa rakakosha mukukura kweatherosclerosis kuburikidza nenzira dzakawanda uye ine hukama hwepedyo nechirwere chemoyo.Enzyme-yakabatana immunosorbent assay (ELISA) ndiyo nzira inonyanya kushandiswa mukutsvagisa kwazvino kwePDGF-BB yekuona puroteni iyi muropa.Semuenzaniso, Yuran Zeng nevamwe vaaishanda navo vakasarudza iyo plasma yePDGF-BB nekushandisa enzyme-yakabatana immunosorbent assay uye vakaona kuti PDGF-BB inobatsira zvakanyanya kune pathogenesis yecarotid atherosclerosis.Muchidzidzo chedu, takatanga taongorora iyo SERS spectra yeakasiyana PDGF-BB aqueous mhinduro ine yakaderera zvakanyanya, tichishandisa yedu 785 nm Raman spectroscopy chikuva.Isu takaona kuti hunhu hwepamusoro neRaman shift ye1509 cm-1 dzakapihwa kune aqueous solution yePDGF-BB.Pamusoro pezvo, isu takaona kuti aya emhando yepamusoro akabatanidzwa zvakare neaqueous solution yePDGF-BB.
Kambani yedu yakabatana nezvikwata zvekutsvagisa zveyunivhesiti kuita SERS spectroscopy ongororo pahuwandu hwemakumi manomwe nesere weti samples.Izvi zvaisanganisira 20 samples kubva kuvarwere vakavhiyiwa PCI, 40 samples kubva kuvarwere vasina kuvhiyiwa PCI, uye 18 samples kubva kuvanhu vane hutano.Isu takaongorora zvine hungwaru iyo weti SERS spectra nekubatanidza maRaman peaks neRaman frequency shift ye1509cm-1, iyo yakabatana zvakananga nePDGF-BB.Tsvagiridzo yakaratidza kuti weti samples dzevarwere vakavhiyiwa PCI vaive nehunhu hunoonekwa hwepamusoro hwe1509cm-1, nepo chinhambwe ichi chaive chisipo mumasampuli eweti evanhu vane hutano uye vazhinji vasiri PCI varwere.Panguva imwecheteyo, pakasanganiswa data yekiriniki yechipatara ye coronary angiography, zvakaonekwa kuti nzira yekuona iyi inoenderana nekuona kana paine kuvharika kwemoyo kunopfuura 70%.Uyezve, nzira iyi inogona kuongorora nekunzwa uye chaiyo ye85% uye 87% zvakateerana, dhigirii rekuvharika rinopfuura 70% muzviitiko zvecoronary artery chirwere nekuona maitiro epamusoro eRaman e1509 cm-1.5%, saka, nzira iyi inotarisirwa kuve hwaro hwakakosha pakusarudza kana varwere vane coronary artery chirwere vachida PCI, ichipa ruzivo rwakanyanya runobatsira rwekutanga kutariswa kwevanofungidzirwa mhosva dze coronary artery chirwere.
Tichifunga nezvemamiriro ezvinhu aya, kambani yedu yakaita zvakabuda patsvagiridzo yedu yekutanga nekutanga Platelet Derived Growth Factor Analyzer.Ichi chishandiso chichashandura zvakanyanya kusimudzirwa uye kushandiswa kwakapararira kwekutanga kwechirwere chemoyo chemoyo.Ichabatsira zvakanyanya mukuvandudzwa kwehutano hwemoyo muChina uye pasi rese.
Bibliography
[1] Huinan Yang, Chengxing Shen, Xiaoshu Cai et al.Isingavasi uye inotarisirwa kuongororwa kwechirwere chemoyo neweti uchishandisa pamusoro-enhanced Raman spectroscopy [J].Muongorori, 2018, 143, 2235–2242.
Parameter mapepa
| nhamba yemuenzaniso | SEB-C100 |
| test chinhu | Kusimba kweplatelet-derived growth factor hunhu hwepamusoro muweti |
| Miedzo Nzira | otomatiki |
| Mutauro | ChiChinese |
| Detection Principle | Raman spectroscopy |
| kutaurirana interface | Micro USB Port, Network Port, WiFi |
| inodzokororwa | Coefficient yekusiyana kwemhedzisiro yebvunzo ≤ 1.0% |
| dhigirii rekururama | Zvigumisiro zvinonyatsoenderana nemuenzaniso wehutano hwezviyero zvinoenderana. |
| kugadzikana | Coefficient of variation ≤1.0% yemuenzaniso wakafanana mukati me8 maawa emagetsi |
| Kurekodha nzira | LCD kuratidza, FlashROM data kuchengetedza |
| nguva yekuziva | Nguva yekuona yemuenzaniso mumwechete isingasviki 120 seconds |
| Simba rekushanda | gadziriso yemagetsi: AC 100V ~ 240V, 50/60Hz |
| zviyero zvekunze | 700mm (L)*560mm(W)*400mm(H) |
| uremu | Zvinenge 75kg |
| nzvimbo yekushanda | kushanda tembiricha: 10℃～30℃;hunyoro hunyoro: ≤90%;air pressure: 86kPa～106kPa |
| Kutakurwa uye nzvimbo yekuchengetedza | kushanda tembiricha: -40℃～55℃;hunyoro hunyoro: ≤95%;air pressure: 86kPa～106kPa |
